A synthetic, acylated research peptide engineered as a triple agonist of the GIP, GLP-1 and glucagon receptors. Supplied as a lyophilised powder exclusively for qualified laboratory research
Retatrutide, also known as LY3437943, is a synthetic 39-amino-acid peptide containing a C20 lipid side chain attached through an AEEA–γ-Glu linker. It was engineered for research into the combined activation of the GIP receptor, GLP-1 receptor and glucagon receptor. Its structure incorporates non-natural amino acids and C-terminal amidation. Retatrutide remains an investigational substance and is not an approved medicinal product.
