Retatrutide
A synthetic, acylated research peptide engineered as a triple agonist of the GIP, GLP-1 and glucagon receptors. Supplied as a lyophilised powder exclusively for qualified laboratory research
Product Overview
Retatrutide, also known as LY3437943, is a synthetic 39-amino-acid peptide containing a C20 lipid side chain attached through an AEEA–γ-Glu linker. It was engineered for research into the combined activation of the GIP receptor, GLP-1 receptor and glucagon receptor. Its structure incorporates non-natural amino acids and C-terminal amidation. Retatrutide remains an investigational substance and is not an approved medicinal product.
Product Specification
The following information is provided for research-catalogue and product specification purposes only. Batch-specific identity, purity, salt form and analytical values should be confirmed against the relevant Certificate of Analysis.
| What it is | Retatrutide, also known as LY3437943, is a synthetic 39-amino-acid peptide containing a C20 lipid side chain attached through an AEEA–γ-Glu linker. It was engineered for research into the combined activation of the GIP receptor, GLP-1 receptor and glucagon receptor. Its structure incorporates non-natural amino acids and C-terminal amidation. Retatrutide remains an investigational substance and is not an approved medicinal product. |
|---|---|
| Sequence | Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-[Lys(AEEA-γGlu-C20 diacid)]-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ |
| Molecular weight | 4731.34 g/mol |
| Product family | GLP / GIP / Glucagon |
| Research classification | Investigational synthetic triple-receptor agonist peptide targeting GIPR, GLP-1R and GCGR. Research-use-only reference material. Not for human or veterinary use, diagnostic procedures, therapeutic use or household use. |
| Form | Lyophilised powder |
| Appearance | White to off-white lyophilised cake or powder |
| Fill quantity | 10mg |
| Container type | Sealed 3 mL glass vial |
| Storage | Store sealed at –20°C, protected from light and moisture. For long-term storage, –80°C is preferred. Allow the sealed vial to reach room temperature before opening to minimise condensation. For laboratory preparations, aliquot where appropriate and avoid repeated freeze–thaw cycles. Always follow the batch-specific COA, SDS and validated laboratory procedures. |
| Synonyms | LY3437943; LY-3437943; NOP2Y096GV; Triple G |
| CAS number | 2381089-83-2 |
| Molecular form / formula | C₂₂₁H₃₄₂N₄₆O₆₈ |
| Molecule form | Synthetic, acylated and C-terminally amidated peptide with a C20 diacid conjugated through an AEEA–γ-Glu linker |
| Purity | ≥99% by RP-HPLC — only publish this if confirmed by the batch-specific COA |
| Analysis method | RP-HPLC for purity and mass spectrometry for identity/molecular mass, as reported on the batch-specific COA |
Certificate of Analysis
Each compound is accompanied by third-party analytical documentation where available. Certificates confirm purity, identity and chromatographic analysis against the supplied batch.
Shipping Information
Orders are typically processed within 1–2 business days of confirmed payment. Estimated delivery within Greece is 1–3 business days after dispatch; international (EU) delivery is typically 5–10 business days. All shipping is tracked and discreet.
Storage & Handling
Store sealed at –20°C, protected from light and moisture. For long-term storage, –80°C is preferred. Allow the sealed vial to reach room temperature before opening to minimise condensation. For laboratory preparations, aliquot where appropriate and avoid repeated freeze–thaw cycles. Always follow the batch-specific COA, SDS and validated laboratory procedures.
| Form | Lyophilised powder |
|---|---|
| Appearance | White to off-white lyophilised cake or powder |
| Container type | Sealed 3 mL glass vial |
| Storage & Handling | Store sealed at –20°C, protected from light and moisture. For long-term storage, –80°C is preferred. Allow the sealed vial to reach room temperature before opening to minimise condensation. For laboratory preparations, aliquot where appropriate and avoid repeated freeze–thaw cycles. Always follow the batch-specific COA, SDS and validated laboratory procedures. |
Research-Use-Only Notice
All products are supplied by Greek Peptides for research use only. They are not licensed as pharmaceuticals and are not promoted as, or intended to diagnose, treat, cure, prevent or mitigate any disease or medical condition in humans or animals. They are not intended for human or animal consumption and are not intended for cosmetic, nutritional or recreational use.
By purchasing, the purchaser confirms that they are a qualified individual acting for legitimate research purposes only and accepts our Terms and Conditions and Research Use Policy.
Greek Peptides supplies research-grade peptides to laboratories and researchers across Greece and the EU, with tracked delivery in 1–7 working days and pricing in euros. Every compound ships with a batch-specific certificate of analysis and is sold strictly for research use only — not for human or veterinary use.
